Xiao et al. found that the expression of UBAP1 decreases during NPC development and progression from normal epithelium of nasopharynx to hyperplastic epithelium of nasopharynx, then, to atypical hyperplastic epithelium of the nasopharynx and finally, to nasopharygeal carcinoma [5]. The gene discussed is UBAP1; the disease is nasopharyngeal carcinoma.