Our results, showing that iAR a) could not be detected in membrane preparations of colon cancer cells (Fig. 5C) and b) that testosterone-HSA effects were manifested even in the presence of the anti-androgen flutamide (Fig 5A, B), imply that the molecular identity of mAR is probably not identical with iAR, targeted to the plasma membrane. This evidence concerns the gene PTPRN2 and malignant colon neoplasm.