They indicate that a) functional mAR are expressed not only in hormone-dependent tumors but also in colon tumors, b) their activation through steroid albumin conjugates induces potent pro-apoptotic responses regulated by cytoskeletal rearrangements, and c) these receptors may represent specific targets for the development of novel drugs, since their activation drastically regresses tumor growth and tumor incidence in vivo. The gene discussed is ALB; the disease is neoplasm.