Ang II infusion also increased creatinine clearance to 80.6 ± 20.7 ml/min, a value similar to pre-sepsis levels (88.7 ± 19.6 ml/min, P > 0.05), while, in the vehicle-treated group, creatinine clearance remained low (46.0 ± 26.0 mL/min; P < 0.0001; Figure 4). Here, AGT is linked to Sepsis.