FASLG and autoimmune polyendocrinopathy: In addition, although the last revised criteria for the classification of APS [1] do not include several well-known features which are associated with APS, we believe that the repetitive detection of aPL antibodies (6 and/or 12 weeks from first testing) has important diagnostic and therapeutic implications as seems to confirm APS diagnosis and subsequently indicates the need of anticoagulation therapy, which can prevent not only future events in the eyes but also episodes in other vital organs [1,2,4,5,10].