The levels of 8 of the 25 proteins, GRN, IGFBP2, THBS1, RARRES2, TIMP1, PPBP, CD14, and NRCAM, were found to be statistically significantly (p<0.05) elevated in newly diagnosed subjects with ovarian cancer compared to controls (Table 1, Figure 5). The gene discussed is IGFBP2; the disease is ovarian carcinoma.