Among these genes are: the TNF-308 allele, which is associated with increased levels of TNFα, is correlated with a greater susceptibility to developing DHF [45], [46]; the wild-type AA MBL2 genotype, which is correlated with increased levels of MBL and increased risk factors for the development of dengue-related thrombocytopenia [47] and the polymorphism of the CD209 promoter [48], which is associated with a decreased expression of DC-SIGN and possibly with a lower susceptibility of dendritic cells to be infected by the dengue virus. Here, TNF is linked to Dengue hemorrhagic fever.