TLR2 has also been shown to play a role in the host response to a number of infections by both Gram-positive and Gram-negative bacteria, including Staphylococcus aureus[71], Streptococcus pneumonia[72], Legionella pneumophila[73], [74], and Porphyromonas gingivalis[75]; it also plays an important role in the responses to a number of bacteria that express an atypical LPS [55]. The gene discussed is TLR2; the disease is infection.