The effects were somewhat stronger when the interaction terms were entered individually (exp(β)=0.33; Pinteraction=0.066 for CYP2C8/9 *1/*4/*1/*1 and exp(β)=3.4; Pinteraction=0.028 for CYP2C8/9 *3/*1/*2/*1). Since CYP2C8*3 and CYP2C9*2 are not in perfect LD, we also examined each SNP separately in women with tumours 21 mm or larger. Here, CYP2C9 is linked to neoplasm.