BRCA1 and anemia (phenotype): BRIP1, located at 17q22, is a Fanconi anaemia gene (FANCJ) (Litman et al, 2005) that directly interacts with the BRCT domain of BRCA1 (Yu et al, 2003) and has a role in DNA damage repair (Bridge et al, 2005; Litman et al, 2005).