MRC1 and neoplasm: The reported incidence of abnormalities in MMR genes in SBA patients has been variable, ranging from 5 to 45% by microsatellite testing and from 0 to 26% by immunohistochemical staining of tumour samples (Hibi et al, 1995; Rashid and Hamilton, 1997; Blaker et al, 2002; Planck et al, 2003; Brueckl et al, 2004; Zhang et al, 2006).