CCBE1 maps to 18q21.32, a common region of loss of heterozygosity (LOH) in ovarian cancer (Takakura et al, 1999; Lambros et al, 2005) that is associated with malignant progression of ovarian cancer (Hauptmann et al, 2002) and high tumour grade and poor survival (Lassus et al, 2001). This evidence concerns the gene CCBE1 and ovarian cancer.