KLK3 and Familial prostate cancer: Studies of this cohort have shown a higher rate of incident prostate cancer in Black men compared with White men (Ben-Shlomo et al, 2008), and although Black men were more likely to work in manual occupations (81 vs 67%) and to live in less-affluent areas, there were no marked differences in knowledge of prostate cancer, in delays before seeking medical attention, in the average prostate-specific antigen (PSA) level at diagnosis, or in levels of comorbidity (Metcalfe et al, 2008).