Our study found no significant differences among the expressions of P-gp, MRP and LRP in GC of different pathological types, in agreement with findings by Shi et al [20], who found that the positive rates of P-gp and LRP were 49.2% and 58%, respectively, and such expression was closely related to clinicopathological staging but not related to tumor differentiation. The gene discussed is PGP; the disease is gastric cancer.