Indications for performing mLLB were a diagnostic work up for indeterminate liver disease (n = 38/34%), staging/grading of chronic hepatitis (all: n = 24/21%, HCV: n = 17/15%, AIH: n = 5/5%, HBV: n = 2/2%), others (all: n = 50/45%, PSC: n = 33/30%, PBC: n = 5/5%, malignant tumour: n = 10/9%, alpha-1 antitrypsin deficiency: n = 2/2%) (Table 1). Here, SERPINA1 is linked to cancer.