Nuclear accumulation of GSK-3β and NF-κB p65 was detected in seven RCC lines: KH39, KU19-20, ACHN, Caki1, Caki2, KRC/Y and A498 (Figure 1B) and was undetectable in normal kidney (Figure 1B). The gene discussed is NFKB1; the disease is renal cell carcinoma.