This has also been further verified by quantitative analysis in which the level of p-PYK2 was significantly higher in PBMCs from SLE patients (0.97 ± 0.31 for inactive and 1.07 ± 0.33 for active), but not in PBMCs from RA patients (0.81 ± 0.34), compared with normal PBMCs (0.77 ± 0.33) (Figure 1B). The gene discussed is PTK2B; the disease is rheumatoid arthritis.