While the distribution of Cldn6 (Figure 6G), Cldn11 (Figure 6H), Cldn12 (Figure 6I) and Cldn18 (Figure 6J) corresponded to the expanded suprabasal compartment of the dermatitis-affected Inv-Cldn6-CΔ196 epidermis, immunostaining was less intense and membranous localization less evident in lower suprabasal layers. Here, CLDN12 is linked to skin disorder.