This result is consistent with previous reports suggesting that LPA2 and LPA3 receptors might contribute to LPA-induced LPA production in ovarian cancer cells, because ovarian cancer cells express high levels of LPA2 and LPA3 receptors whereas normal ovarian epithelial cells express low levels of LPA2 and LPA3 receptors [41-43]. This evidence concerns the gene LPAR2 and ovarian cancer.