To test the impact of class I HDAC expression in human pancreatic carcinoma in vivo and to elucidate possible interactions of HDACs and RelA/p65 we evaluated the expression of class I HDACs 1, 2 and 3 by immunohistochemistry and correlated expression data with clinico-pathological features, patient prognosis as well as RelA/p65 expression and nuclear translocation, which has been determined in a previous study in an overlapping cohort [18]. This evidence concerns the gene RELA and exocrine pancreatic carcinoma.