PROS1 and cancer: Recently, considerable effort has been spent in this area of research.10,25–27 We focused our attention on a transcript that is ubiquitously expressed that encodes bladder cancer-associated protein (BLCAP) also known as BC10 protein (bladder cancer-10 kDa protein) that is an 87 amino acid protein with 2 hypothetical transmembrane regions (TM).28,29 Importantly, it has been shown that the mRNA of BLCAP is downregulated in bladder invasive carcinoma28 and in renal cell carcinoma30 and in primary cervical carcinoma,31 underlining the potential onco-suppressive role of this protein.