While only 2.4% of epithelial cells from normal prostate glands show low levels of co-localization between PTEN and BMI1 (Fig 7, Table 1), 37.6% and 18.5% of PIN and carcinoma cells display extensive co-localization between PTEN and BMI1 (Fig 7, Table 1). Here, PTEN is linked to prostate intraepithelial neoplasia.