Hyperinsulinemia also proved to be an important alteration, occurring in 55.5% of the cases, which was also reported by Mangabeira Albernaz and Fukuda18, who found hyperinsulinemia in 86% of the patients with inner ear disorders and clinical suspicion of metabolic etiology, and by D'Avila and Lawinsky25 who found hyperinsulinemia in 72% of the cases with Ménière's syndrome investigated by means of the five-hour glucose-insulin index. This evidence concerns the gene INS and hyperinsulinism.