The administration of chlordiazepoxide (CDZ, 7.5 mg/kg/ip) to Eno2-ΔGR/EGFP bigenic mice largely reversed the anxiety-related phenotype observed in Eno2-ΔGR/EGFP bigenic mice treated with vehicle (Figure 6E–G, E: t7 = 4.102 p<0.0045; F: t7 = 4.840 p<0.0019; G: t7 = 1.724 p>0.127). This evidence concerns the gene ENO2 and Anxiety.