Moreover, this study found significant upregulation of well-known psoriasis-related genes such as β-defensin 2, CD68, and cytokines IL-8 (CXCL8), SCYA2 (MCP-1/CCL2), and platelet-derived endothelial cell growth factor 1 in psoriatic skin lesions. This evidence concerns the gene CXCL8 and psoriasis.