CRP and Sepsis: Gogos et al. concluded from their study that an elevated serum TNF-α level was associated with death, and higher levels of TNF-α and IL-6 were detected in patients with an early hemodynamic deterioration.[8] A significant decrease in the IL-6 level was observed over the study period by Presterl et al. in the survivor group only (P<0.05).[9] Plotkin from their study for sepsis marker dynamics reported that fast kinetics of C-reactive protein and procalcitonin made it impossible to assess the prognosis and effectiveness of treatment of sepsis using these markers.