Correlation among rCBV, MVD, and VEGF confirms that rCBV is a measure of angiogenesis in the cellular fraction of brain tuberculomas.[41] In a recent DCE-MRI study in brain tuberculomas, authors have reported a significant positive correlation between the physiological indices (ktrans and ve) and matrix metalloproteinase 9 (MMP-9) expression (a marker of BBB disruption) in excised tuberculomas. The gene discussed is MMP9; the disease is central nervous system tuberculosis.