According to our rules, JUP, CD24, PRKCD, MAPK13, TACSTD2, DKFZP564O0823 protein, TACSTD1, CEACAM1, XBP1, TTF1, SFTPB, AGR2, ELF3, EVI1, and CDA are highly expressed in ADCA, while EGF, SPTAN1, FLNC, PTGIS, FBXL7, CD200, AP2 M1, ANXA8, HAS1, CALB2, GFPT2, KIAA0427, C1S, EIF4G3, TGM1, Adamts3, hypothetical protein dJ465N24.2.1, and AP3S1 are highly expressed in mesothelioma. This evidence concerns the gene C1S and mesothelioma.