According to our rules, JUP, CD24, PRKCD, MAPK13, TACSTD2, DKFZP564O0823 protein, TACSTD1, CEACAM1, XBP1, TTF1, SFTPB, AGR2, ELF3, EVI1, and CDA are highly expressed in ADCA, while EGF, SPTAN1, FLNC, PTGIS, FBXL7, CD200, AP2 M1, ANXA8, HAS1, CALB2, GFPT2, KIAA0427, C1S, EIF4G3, TGM1, Adamts3, hypothetical protein dJ465N24.2.1, and AP3S1 are highly expressed in mesothelioma. The gene discussed is AP3S1; the disease is mesothelioma.