The expression rate of CD40 in gastric cancer tissues was significantly stronger (P < 0.01) than that in normal tissues (Table 1 and Figures 1A, B); Positive expression of CD138 in tumour and normal tissues was observed in 44.6% and 96.9% of cases, respectively (Table 1 and Figures 1C, D); Positive expression of Gelsolin in tumour and normal tissues was observed in 10.7% and 81.3% of cases, respectively (Table 1 and Figures 1E, F); Positive expression of P53 and P65 in tumour tissues was observed in 69.6% and 64.3% of cases, respectively (Table 1 and Figures 1G, H, I, J). The gene discussed is TP53; the disease is gastric cancer.