Finally, WAGR syndrome (OMIM 194072), which includes Wilms’ tumor, aniridia, genitourinary anomalies, and mental retardation, is caused by either microscopic or submicroscopic deletion of chromosome 11p13-p12 in a region containing both the Wilms tumor 1, WT1 gene and the PAX6 genes. The gene discussed is PAX6; the disease is isolated aniridia.