UCHL1 and renal cell carcinoma: In MZ1851RC cells for example the UCHL1 promoter DNA was not methylated, whereas the COBRA-based analysis indicated a partial methylation of the UCHL1 promoter DNA in the RCC cell line MZ2862RC, characterized by methylation of some of the CpG dinucleotides within the core region of the UCHL1 promoter while other CpG sites remain unmethylated.