A recent report also revealed that CD36-deficient mice showed impaired tumor necrosis factor-alpha (TNF-α) secretion in response to glycosylphosphatidylinositol (GPI) from P. falciparum and higher parasitemia levels and mortality when infected with Plasmodium chabaudi chabaudi AS (P. chabaudi chabaudi AS) [18]. This evidence concerns the gene TNF and parasitic infectious disease.