Histopathological findings in group II patients showed pauci-immune crescentic glomerulonephritis as the commonest finding seen in three cases (21.4%), acute tubulointerstitial nephritis and hypertensive changes each in 2 cases (14.3%), IgA nephropathy with mesangial IgA deposits in one case (7.1%), immune complex mediated membranoproliferative glomerulonephritis (MPGN) with immune deposits of C3, IgM and IgG in the mesangium and peripheral capillary loops in one case (7.1%), fibrillary glomerulonephritis with mesangial deposits of C3, IgG, IgA and IgM was seen in one patient (7.1%). The gene discussed is C3; the disease is primary membranoproliferative glomerulonephritis.