SERPINA1 and hyperinsulinemic hypoglycemia, familial, 4: The highest concentration of porphyrins, 1.4 μmol/24 hour (reference limit < 0.6) and 0.26 mol/mol creatinine (reference limit < 0.04), was found in a patient with HCC and liver cirrhosis related to alpha-1-antitrypsin deficiency.