We examined the miR-483* genomic DNA location because miR-483* showed the greatest reduction in expression in maternal HF fed offspring, and found that miR-483* was encoded in an intron of Igf2. As intronic miRNAs may share common promoters as their host genes, many intronic miRNAs show significantly correlated expression profiles with their host genes[50,51]. The gene discussed is IGF2; the disease is hydrops fetalis.