CD4 and infection: An additional group of animals that received 104 SMARTA cells prior to infection with rCVB3.6 showed, as expected, a higher percentage of I-Ab/GP66–77 tetramer+CD4+CD8− T cells (∼1% above background) compared to rCVB3.6-infected mice that had not received SMARTA cells (Figure 8B); these tetramer+ cells were mostly CD45.1+ (SMARTA) cells (data not shown).