The great majority of rCVB3-specific SMARTA cells had an effector phenotype (CD44hi CD62Llo CD127lo) (Figure 4D), which was similar to LCMV-specific SMARTA cells, indicating that primary CD4+ T cells induced by rCVB3.6 infection, although low in quantity, appear to be normal in quality; additional qualitative studies are presented later in this report (see Figure eight). Here, CD4 is linked to infection.