Among other genetic syndromes, mutations in GLI3 are found in patients with Greig-cephalopolysyndactyly-syndrome (GCPS [MIM175700]) [11], [12], Pallister-Hall syndrome (PHS [MIM146510]) [13], [14] and - in one patient - acrocallosal syndrome [MIM200990] [15]. Here, GLI3 is linked to Greig cephalopolysyndactyly syndrome.