In agreement with this observation, differential expression of several genes in set #2 has also been associated with breast cancer metastasis, to the bone (CX3CL1, FARSLA, FST, GBP2, HLADPA1, HLADPB1, HLADRB1, MITF, NEDD4L, SERPINA1 and TGFBI) (Kang et al, 2005) or to the lung (ALDH3A1, COL1A1, EFEMP1, GSN, HLADPA1, HLADPB1, MAN1A1, PTPRN2 and TNC) (Minn et al, 2005). This evidence concerns the gene SERPINA1 and breast cancer.