In agreement with this observation, differential expression of several genes in set #2 has also been associated with breast cancer metastasis, to the bone (CX3CL1, FARSLA, FST, GBP2, HLADPA1, HLADPB1, HLADRB1, MITF, NEDD4L, SERPINA1 and TGFBI) (Kang et al, 2005) or to the lung (ALDH3A1, COL1A1, EFEMP1, GSN, HLADPA1, HLADPB1, MAN1A1, PTPRN2 and TNC) (Minn et al, 2005). The gene discussed is MAN1A1; the disease is breast cancer.