These good prognosis tumours were mainly characterised by over-expression of ERBB3 and down-regulation of cell cycle-related genes such as CCNA2 and CCNB2. Notably, ERBB3 expression has recently been associated with favorable clinical outcome of invasive ductal carcinomas (Lee et al, 2007). This evidence concerns the gene ERBB3 and invasive ductal breast carcinoma.