Our measurement of PTH did not take into account factors that could affect analysis: age, gender, menopausal status, vitamin D and calcium supplementation, smoking, alcohol consumption, steroid use, family history of osteoporosis, physical activity, drugs to control bone and calcium metabolism, rheumatoid arthritis, other diseases that cause secondary osteoporosis, levels of sex hormones, etc. Further studies will be needed to clarify all of these variables in relation to PTH's effects on the aging brain and aging skeleton. This evidence concerns the gene PTH and osteoporosis.