VEGFA and testicular hydrocele: Secretion of VEGF-A molecules in the scrotal region of hydrocele patients could be responsible for: (i) extravasation and accumulation of fluids, plasma, lymph, etc. from the blood and lymphatic vessels into the scrotal region, resulting in the formation of hydrocele, chylocele and lymphocele; (ii) formation of nodules in hydrocele patients which are usually observed just before hydrocele development when DEC is administered (61).