The prevalence of anti-TPO in children with T1DM has been reported to be between 10% and 29.4% and that of anti-Tg between 8.7% and 14.4% (8,23–25), while the coexistence of both anti-thyroid antibodies has been reported in 5.9%–7% of the patients (8,24,25). The gene discussed is TG; the disease is type 1 diabetes mellitus.