FOXF1 and Esophageal atresia: Patients with deletions spanning the entire FOX cluster (FOXF1, MTHFSD, FOXC2 and FOXL1) at 16q24.1 (these are hereinafter referred to as ‘whole cluster deletions’) have, in addition to ACD/MPV, esophageal atresia, tracheo-esophageal fistula, and other gastro-intestinal tract atresias (duodenal and anal atresia).