Following our report, a recent study declared that these CD4+CD25-Foxp3+ T cells functionally resembled conventional Tregs by fluorescence-activated cell sorting (FACS) CD4+CD25-CD127- T cells as a substitute for CD4+CD25-Foxp3+ T cells from SLE patients [11]. The gene discussed is FOXP3; the disease is systemic lupus erythematosus.