ADIPOQ and chronic kidney disease: Analogous results have been observed in a study by Becker et al, from the Mild to Moderate Kidney study database in non-diabetic subjects with primarily stage 3 to 4 CKD [10], where patients who developed new cardiovascular events had significantly lower adiponectin levels (odds ratio, 0.72; 95% CI 0.58 to 0.89; P = 0.002).