Another chemokine ligand of the CXCR2 receptor, CXCL8, has also been implicated in tumourigenesis by enhancing melanoma cell proliferation [17], alveolar epithelial neoplasia [18] and breast cancer development [19], however its expression and role in endometrial adenocarcinoma is unclear. The gene discussed is CXCL8; the disease is endometrium adenocarcinoma.