Meanwhile, after the same 8 Gy dose, the uptake of radio-labeled annexin V as well as the number of apoptotic cells detected by TUNEL in S180 sarcoma tumor was significantly lower than that in EL4 lymphoma, indicating that the different response to radiation between these two tumor types might be correlated with the difference in early phase apoptosis. The gene discussed is ANXA5; the disease is sarcoma.