MUC1 and neoplasm: Snijdewint et al. [11] demonstrated ADCC elicited by AS1402 in vitro in the breast tumor cell line ZR-75-1, in three bone marrow-derived tumor cell lines from breast cancer patients (KM22, 1590, HG15), and in Chinese hamster ovary (CHO) cells transfected with the human MUC1 gene, by using peripheral blood mononuclear cells (PBMCs) from healthy donors.