BCL2 and stroke disorder: Results revealed that Bcl-2 immunoreactivity was significantly increased in the brains of stroke animals that were treated with low dose minocycline, especially within the striatum ipsilateral to the occluded MCA (20 mg/kg: 9.83 ± 1.50 density/0.05 mm2) relative to vehicle-treated stroke animals (0.235 ± 0.112 cells/0.05 mm2) (F2,15 = 37.151; p < 0.0001) (Figure 6A, B, D).