TIMP1 and Sepsis: The most relevant findings were the following: (a) higher serum levels of MMP-10 and TIMP-1, and nonsignificantly higher MMP-9 levels in sepsis patients than in healthy controls; (b) a significant correlation between MMP-9, MMP-10, TIMP-1, and several indicators of severity in sepsis, including biomarkers of coagulation, lactic acid, APACHE-II, and SOFA scores; and (c) the nonsurviving sepsis patients had higher TIMP-1 levels, lower MMP-9/TIMP-1 ratios, and nonsignificantly higher MMP-10 levels than did surviving patients.