For example, several studies have previously reported inconsistent results regarding the prognostic impact of different oncogenic pathways in GC - the prognostic implications of proliferation-related antigens such as Ki-67 in GC are not firmly established [29], and high NF-κB activation in GC has been associated with both good and bad GC patient outcome in different studies [7],[30]. This evidence concerns the gene NFKB1 and gastric cancer.