APOE and Alzheimer disease: The higher risk conferred by allele APOE ε4 was observed even when the samples were subgrouped by sex: MCI women (OR = 2.46, 95%CI 1.45-4.15 p < 0.001) versus AD women (OR = 5.10, 95%CI 3.20-8.13 p < 0.01) and MCI men (OR = 2.59, 95%CI 1.36-4.92 p < 0.04) versus AD men (OR = 3.19, 95%CI 1.72-5.91 p < 0.001).